CTD110.6

Antibody IDAN0022
Epitope ID EP0004
Epitope nameO-GlcNAc
Recognition regionGlcNAc(b1-)Ser/Thr
Immunoprecipitation[1][2][3]
Immunoblot[1][4*][2][5*][6][7][8][9]
ELISA/RIA
Flow cytometry
Histochemistry[9]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogen
AvailabilityCovance Research Products,Inc.
Santa Cruz Biotechnology, Inc.
Applications
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1 Comer FI, Vosseller K, Wells L, Accavitti MA, Hart GW.
Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.
Anal Biochem. 2001 Jun 15;293(2):169-77
PMID: 11399029
2 Park SY, Ryu J, Lee W.
O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes.
Exp Mol Med. 2005 Jun 30;37(3):220-9
PMID: 16000877
3 Walgren JL, Vincent TS, Schey KL, Buse MG.
High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.
Am J Physiol Endocrinol Metab. 2003 Feb ;284(2):E424-34
PMID: 12397027
4 Parker G, Taylor R, Jones D, McClain D.
Hyperglycemia and inhibition of glycogen synthase in streptozotocin-treated mice: role of O-linked N-acetylglucosamine.
J Biol Chem. 2004 May 14;279(20):20636-42
PMID: 15014073
5 Kneass ZT, Marchase RB.
Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc.
J Biol Chem. 2004 Oct 29;279(44):45759-65
PMID: 15322139
6 Nagy T, Champattanachai V, Marchase RB, Chatham JC.
Glucosamine inhibits angiotensin II-induced cytoplasmic Ca2+ elevation in neonatal cardiomyocytes via protein-associated O-linked N-acetylglucosamine.
Am J Physiol Cell Physiol. 2006 Jan ;290(1):C57-65
PMID: 16107505
7 Dauphinee SM, Ma M, Too CK.
Role of O-linked beta-N-acetylglucosamine modification in the subcellular distribution of alpha4 phosphoprotein and Sp1 in rat lymphoma cells.
J Cell Biochem. 2005 Oct 15;96(3):579-88
PMID: 16052526
8 Ball LE, Berkaw MN, Buse MG.
Identification of the major site of O-GlcNAc modification in the C-terminus of IRS-1.
Mol Cell Proteomics. 2005 Oct 22;[Epub ahead of print]:
PMID: 16244361
9 Akimoto Y, Comer FI, Cole RN, Kudo A, Kawakami H, Hirano H, Hart GW.
Localization of the O-GlcNAc transferase and O-GlcNAc-modified proteins in rat cerebellar cortex.
Brain Res. 2003 Mar 21;966(2):194-205
PMID: 12618343