CTD110.6
| Antibody ID | AN0022 |
|---|
| Epitope ID | EP0004 |
|---|---|
| Epitope name | O-GlcNAc |
| Recognition region | GlcNAc(b1-)Ser/Thr |
| Immunoprecipitation | [1][2][3] |
| Immunoblot | [1][4*][2][5*][6][7][8][9] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [9] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | Covance Research Products,Inc. Santa Cruz Biotechnology, Inc. |
| Applications |
| 1 | Comer FI, Vosseller K, Wells L, Accavitti MA, Hart GW. Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine. Anal Biochem. 2001 Jun 15;293(2):169-77 PMID: 11399029 |
|---|---|
| 3 | Walgren JL, Vincent TS, Schey KL, Buse MG. High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin. Am J Physiol Endocrinol Metab. 2003 Feb ;284(2):E424-34 PMID: 12397027 |
| 9 | Akimoto Y, Comer FI, Cole RN, Kudo A, Kawakami H, Hirano H, Hart GW. Localization of the O-GlcNAc transferase and O-GlcNAc-modified proteins in rat cerebellar cortex. Brain Res. 2003 Mar 21;966(2):194-205 PMID: 12618343 |
| 4 | Parker G, Taylor R, Jones D, McClain D. Hyperglycemia and inhibition of glycogen synthase in streptozotocin-treated mice: role of O-linked N-acetylglucosamine. J Biol Chem. 2004 May 14;279(20):20636-42 PMID: 15014073 |
| 5 | Kneass ZT, Marchase RB. Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc. J Biol Chem. 2004 Oct 29;279(44):45759-65 PMID: 15322139 |
| 2 | Park SY, Ryu J, Lee W. O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes. Exp Mol Med. 2005 Jun 30;37(3):220-9 PMID: 16000877 |
| 7 | Dauphinee SM, Ma M, Too CK. Role of O-linked beta-N-acetylglucosamine modification in the subcellular distribution of alpha4 phosphoprotein and Sp1 in rat lymphoma cells. J Cell Biochem. 2005 Oct 15;96(3):579-88 PMID: 16052526 |
| 8 | Ball LE, Berkaw MN, Buse MG. Identification of the major site of O-GlcNAc modification in the C-terminus of IRS-1. Mol Cell Proteomics. 2005 Oct 22;[Epub ahead of print]: PMID: 16244361 |
| 6 | Nagy T, Champattanachai V, Marchase RB, Chatham JC. Glucosamine inhibits angiotensin II-induced cytoplasmic Ca2+ elevation in neonatal cardiomyocytes via protein-associated O-linked N-acetylglucosamine. Am J Physiol Cell Physiol. 2006 Jan ;290(1):C57-65 PMID: 16107505 |