Leo Mel 13
| Antibody ID | AN0416 |
|---|
| Epitope ID | EP0062 |
|---|---|
| Epitope name | N-Acetyl GD3 |
| Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal(b1-)-R GalNAc(b1-4)[Neu5Ac(a2-8)Neu5Ac(a2-3)]Gal(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [1*] |
| ELISA/RIA | |
| Flow cytometry | [2] |
| Histochemistry | [2] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM(k) |
| Immunogen | |
| Availability | |
| Applications |
| 1 | Fukuta S, Werkmeister JA, Burns GF, Ginsburg V, Magnani JL. Monoclonal antibody Leo Mel 3, which inhibits killing of human melanoma cells by anomalous killer cells, binds to a sugar sequence in GD2 (II3(NeuAc)2-GgOse3Cer) and several other gangliosides. J Biol Chem. 1987 Apr 5;262(10):4800-3 PMID: 2435716 |
|---|---|
| 2 | Werkmeister JA, Triglia T, Mackay IR, Dowling JP, Varigos GA, Morstyn G, Burns GF. Fluctuations in the expression of a glycolipid antigen associated with differentiation of melanoma cells monitored by a monoclonal antibody, Leo Mel 3. Cancer Res. 1987 Jan 1;47(1):225-30 PMID: 3791209 |