Heparan Sulfate

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0086

Epitope IDEP0086
Epitope nameHeparan Sulfate
Structure
Sequence-[{[±(HSO3(-2))GlcA(b1-4)]or[±(HSO3(-2))IdoA(a1-4)]}(±(HSO3(-3))±[(HSO3 or CH3CO)(-2)]±(HSO3(-6))GlcN]n-
Aliases
History
DB
Molecular weight
Composition-
Species

Bos taurus
Homo sapiens
Mus musculus
Rattus norvegicus
Tissue and Cellular distribution

aorta(bovine)
aorta(human)
basement membrane
englebreth-holm-schwarz tumor/EHS-HS(mouse)
escherichia coli K5 capsular polysaccharide/K5PS
glomerular basement membrane/GBM
intestine(bovine)
kidney(bovine)
lung(bovine)
Subcellular distribution
Developmental change
Cell line

HEK293/human embryonic kidney[23*]
Receptor

L-Selectin
P-Selectin
Function

Heparan sulfate proteoglycans (HSPGs) play crucial roles regulating key developmental signaling pathways, such as the Wnt, Hedgehog, transforming growth factor-beta, and fibroblast growth factor pathways.[1]
Diseases
Application
Comment