Dimeric Lewis a

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0090

Epitope IDEP0090
Epitope nameDimeric Lewis a
Structure
SequenceGal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
AliasesDimeric Lea
History
DB GlyTouCan:G21808VY JCGGDB
Molecular weight1041.0
Composition(Fuc)2(Gal)2(GlcNAc)2
Species

Homo sapiens
Tissue and Cellular distribution

cancer/stomach(human)
Subcellular distribution
Developmental change
Cell line

COLO 201/human colon adenocarcinoma
COLO 205/human colon adenocarcinoma
HT-29/human colon adenocarcinoma
WiDr/human colon adenocarcinoma
Receptor
Function

cancer-associated antigen
Diseases

gastric cancer

The induction of apoptosis may play a key role in the direct antitumour activity of the murine monoclonal antibody NCC-ST-421 (ST-421) on Colo 205 cells.[2]
Application
Comment