GT1a alpha

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0111

Epitope IDEP0111
Epitope nameGT1a alpha
Structure
SequenceNeu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer
AliasesChol-1 alpha-a
HistoryCholinergic-specific antigens termed the Chol-1 family have been suggested to be of a ganglioside nature by Richardson et al. The chemical structure of Chol-1 alpha-a was determined for the first time, being as follows: IV3NeuAc III6NeuAc II3NeuAc-GgOse4 Cer.[2][3]
DB GlyTouCan:G02149VR JCGGDB
Molecular weight1872.7(Cer)
Composition(Gal)2(GalNAc)1(Glc)1(Neu5Ac)4(Cer)1
Species

Bos taurus[3]
Rattus norvegicus[4]

Tissue and Cellular distribution

brain(bovine)[3]
central nervous system(rat)[4]

Subcellular distribution

Developmental change

Cell line

Receptor

Function

GT1a alpha was a cholinerginic-specific antigen.

Diseases

Application
Comment