WGHS-29-1
| Antibody ID | AN0550 |
|---|
| Epitope ID | EP0011 |
|---|---|
| Epitope name | Lewis x |
| Recognition region | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [1*][2][3] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | |
| Applications |
| 1 | Holmes EH, Hakomori S, Ostrander GK. Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase. J Biol Chem. 1987 Nov 15;262(32):15649-58 PMID: 2960671 |
|---|---|
| 2 | Huang LC, Brockhaus M, Magnani JL, Cuttitta F, Rosen S, Minna JD, Ginsburg V. Many monoclonal antibodies with an apparent specificity for certain lung cancers are directed against a sugar sequence found in lacto-N-fucopentaose III. Arch Biochem Biophys. 1983 Jan ;220(1):318-20 PMID: 6830241 |
| 3 | Holmes EH, Ostrander GK, Clausen H, Graem N. Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation. J Biol Chem. 1987 Aug 15;262(23):11331-8 PMID: 3112156 |