KM93
| Antibody ID | AN0178 |
|---|
| Epitope ID | EP0012 |
|---|---|
| Epitope name | Sialyl Lewis x |
| Recognition region | Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [1][5][9] |
| ELISA/RIA | [7][8][5] |
| Flow cytometry | |
| Histochemistry | [2][3][4][6][10] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | lung adenocarcinoma tissues[8] |
| Availability | Calbiochem KYOWA HAKKO KOGYO Co., Ltd. KAMIYA BIOMEDICAL COMPANY Millipore Abnova |
| Applications |
| 1 | Priest R, Bird MI, Malhotra R. Characterization of E-selectin-binding epitopes expressed by skin-homing T cells. Immunology. 1998 Aug ;94(4):523-8 PMID: 9767440 |
|---|---|
| 2 | Farmer RW, Richtsmeier WJ, Scher RL. Identification of sialyl Lewis-x in squamous cell carcinoma of the head and neck. Head Neck. 1998 Dec ;20(8):726-31 PMID: 9790295 |
| 3 | Tsuji T, Kimura Y, Murakami T, Sasaki K, Shinozaki F. [An immunohistochemical evaluation of Warthin's tumor using the monoclonal anti-human lung adenocarcinoma antibody KM-93 and the anti-human gastric carcinoma antibody KM-231] Gan No Rinsho. 1990 Jun ;36(7):783-6 PMID: 2355463 |
| 4 | Tsuzi T, Shinozaki F, Yamada K, Mori M. Immunohistochemical detection of human lung and gastric cancer antigen in human salivary gland tumors. Anticancer Res. 1989 Mar ;9(2):327-39 PMID: 2665633 |
| 5 | Dohi T, Nemoto T, Ohta S, Shitara K, Hanai N, Nudelman E, Hakomori S, Oshima M. Different binding properties of three monoclonal antibodies to sialyl Le(x) glycolipids in a gastric cancer cell line and normal stomach tissue. Anticancer Res. 1993 Sep ;13(5A):1277-82 PMID: 8239497 |
| 6 | Croce MV, Isla-Larrain M, Tur R, Rabassa ME, Segal-Eiras A. Antigenic differences between metastatic cells in bone marrow and primary tumours and the anti-MUC1 humoral immune response induced in breast cancer patients. Clin Exp Metastasis. 2004 ;21(2):139-47 PMID: 15168731 |
| 7 | Shitara K, Hanai N, Yoshida H. Distribution of lung adenocarcinoma-associated antigens in human tissues and sera defined by monoclonal antibodies KM-52 and KM-93. Cancer Res. 1987 Mar 1;47(5):1267-72 PMID: 3545444 |
| 8 | Hanai N, Shitara K, Yoshida H. Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung. Cancer Res. 1986 Sep ;46(9):4438-43 PMID: 3731100 |
| 9 | Dohi T, Abe K, Ohshiba S, Yamaguchi K, Oshima M. Immunohistological and biochemical detection of fucosylated polylactosamine antigen with monoclonal antibody ACFH18 in gastric cancer and normal gastric mucosa. Jpn J Cancer Res. 1990 Jun ;81(6-7):676-81 PMID: 2119368 |
| 10 | Croce MV, Isla-Larrain M, Rabassa ME, Demichelis S, Colussi AG, Crespo M, Lacunza E, Segal-Eiras A. Lewis x is highly expressed in normal tissues: a comparative immunohistochemical study and literature revision. Pathol Oncol Res. 2007 ;13(2):130-8 PMID: 17607374 |