B72.3
| Antibody ID | AN0084 |
|---|
| Epitope ID | EP0022 |
|---|---|
| Epitope name | Sialyl Tn Antigen |
| Recognition region | Neu5Ac(a2-6)GalNAc(a1-)Ser/Thr |
| Immunoprecipitation | |
| Immunoblot | |
| ELISA/RIA | [7] |
| Flow cytometry | |
| Histochemistry | [1][4][5][3][6][2][8][9] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgG1 |
| Immunogen | membrane-enriched fraction of a human breast carcinoma liver metastasis |
| Availability | abcam |
| Applications |
| 1 | Itzkowitz SH, Yuan M, Montgomery CK, Kjeldsen T, Takahashi HK, Bigbee WL, Kim YS. Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer. Cancer Res. 1989 Jan 1;49(1):197-204 PMID: 2908846 |
|---|---|
| 2 | Xu M, Real FX, Welt S, Schussler MH, Oettgen HF, Old LJ. Expression of TAG-72 in normal colon, transitional mucosa, and colon cancer. Int J Cancer. 1989 Dec 15;44(6):985-9 PMID: 2481651 |
| 3 | Vierbuchen MJ, Fruechtnicht W, Brackrock S, Krause KT, Zienkiewicz TJ. Quantitative lectin-histochemical and immunohistochemical studies on the occurrence of alpha(2,3)- and alpha(2,6)-linked sialic acid residues in colorectal carcinomas. Relation to clinicopathologic features. Cancer. 1995 Sep 1;76(5):727-35 PMID: 8625173 |
| 4 | Ikeda Y, Kuwano H, Baba K, Ikebe M, Matushima T, Adachi Y, Mori M, Sugimachi K. Expression of Sialyl-Tn antigens in normal squamous epithelium, dysplasia, and squamous cell carcinoma in the esophagus. Cancer Res. 1993 Apr 1;53(7):1706-8 PMID: 8453646 |
| 5 | Smith S. Becoming an independent homebirth midwife. Aust Coll Midwives Inc J. 1994 Dec ;7(4):27-9 PMID: 7887817 |
| 6 | Kinney AY, Sahin A, Vernon SW, Frankowski RF, Annegers JF, Hortobagyi GN, Buzdar AU, Frye DK, Dhingra K. The prognostic significance of sialyl-Tn antigen in women treated with breast carcinoma treated with adjuvant chemotherapy. Cancer. 1997 Dec 15;80(12):2240-9 PMID: 9404700 |
| 7 | Kjeldsen T, Clausen H, Hirohashi S, Ogawa T, Iijima H, Hakomori S. Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope. Cancer Res. 1988 Apr 15;48(8):2214-20 PMID: 2450649 |
| 8 | Johnston WW, Szpak CA, Lottich SC, Thor A, Schlom J. Use of a monoclonal antibody (B72.3) as a novel immunohistochemical adjunct for the diagnosis of carcinomas in fine needle aspiration biopsy specimens. Hum Pathol. 1986 May ;17(5):501-13 PMID: 2422108 |
| 9 | Barbera-Guillem E, Nyhus JK, Wolford CC, Friece CR, Sampsel JW. Vascular endothelial growth factor secretion by tumor-infiltrating macrophages essentially supports tumor angiogenesis, and IgG immune complexes potentiate the process. Cancer Res. 2002 Dec 1;62(23):7042-9 PMID: 12460925 |