DMAb-1

Antibody IDAN0504
Epitope ID EP0051
Epitope nameN-Acetyl GM2
Recognition regionGalNAc(b1-4)[Neu5Ac(a2-3)]Gal-R
Immunoprecipitation
Immunoblot[2][3]
ELISA/RIA[2][3]
Flow cytometry
Histochemistry[4]
Comment
Epitope ID EP0311
Epitope nameGalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1)
Recognition regionGalNAc(b1-4)[Neu5Ac(a2-3)]Gal-R
Immunoprecipitation
Immunoblot[2][3]
ELISA/RIA[2][3]
Flow cytometry
Histochemistry[4]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogen
Availability
ApplicationsTLC-ELISA[1*]
Up  Down
1 Fredman P, Mansson JE, Wikstrand CJ, Vrionis FD, Rynmark BM, Bigner DD, Svennerholm L.
A new ganglioside of the lactotetraose series, GalNAc-3'-isoLM1, detected in human meconium.
J Biol Chem. 1989 Jul 25;264(21):12122-5
PMID: 2473071
2 Karlsson G, Mansson JE, Wikstrand C, Bigner D, Svennerholm L.
Characterization of the binding epitope of the monoclonal antibody DMAb-1 to ganglioside GM2.
Biochim Biophys Acta. 1990 Apr 17;1043(3):267-72
PMID: 1691018
3 Vrionis FD, Wikstrand CJ, Fredman P, Mansson JE, Svennerholm L, Bigner DD.
Five new epitope-defined monoclonal antibodies reactive with GM2 and human glioma and medulloblastoma cell lines.
Cancer Res. 1989 Dec 1;49(23):6645-51
PMID: 2479468
4 Hedberg KM, Mahesparan R, Read TA, Tysnes BB, Thorsen F, Visted T, Bjerkvig R, Fredman P.
The glioma-associated gangliosides 3'-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains.
Neuropathol Appl Neurobiol. 2001 Dec ;27(6):451-64
PMID: 11903928