MK2-34

Antibody IDAN0118
Epitope ID EP0052
Epitope nameN-Glycolyl GM2
Recognition regionGalNAc(b1-4)[Neu5Gc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Immunoprecipitation
Immunoblot[1][2]
ELISA/RIA[3][2]
Flow cytometry
Histochemistry[1]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
ImmunogenGM2(NeuGc)[2]
AvailabilitySEIKAGAKU BIOBUSINESS CORPORATION -English
SEIKAGAKU BIOBUSINESS CORPORATION -Japanese
Applications
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1 Miyake M, Hashimoto K, Ito M, Ogawa O, Arai E, Hitomi S, Kannagi R.
The abnormal occurrence and the differentiation-dependent distribution of N-acetyl and N-glycolyl species of the ganglioside GM2 in human germ cell tumors. A study with specific monoclonal antibodies.
Cancer. 1990 Feb 1;65(3):499-505
PMID: 2153431
2 Miyake M, Ito M, Hitomi S, Ikeda S, Taki T, Kurata M, Hino A, Miyake N, Kannagi R.
Generation of two murine monoclonal antibodies that can discriminate N-glycolyl and N-acetyl neuraminic acid residues of GM2 gangliosides.
Cancer Res. 1988 Nov 1;48(21):6154-60
PMID: 3167861
3 Zenita K, Hirashima K, Shigeta K, Hiraiwa N, Takada A, Hashimoto K, Fujimoto E, Yago K, Kannagi R.
Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages.
J Immunol. 1990 Jun 1;144(11):4442-51
PMID: 2111348