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Antibody IDAN0580
Epitope ID EP0061
Epitope nameGD2
Recognition regionGalNAc(b1-4)[Neu5Ac(a2-8)Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Immunoprecipitation
Immunoblot[2][1][3]
ELISA/RIA[2][1][3][4]
Flow cytometry[4]
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
ImmunogenLAN-1/human neuroblastoma[2]
AvailabilityATCC
Applications
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1 Cheresh DA, Harper JR, Schulz G, Reisfeld RA.
Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells.
Proc Natl Acad Sci U S A. 1984 Sep ;81(18):5767-71
PMID: 6385004
2 Schulz G, Cheresh DA, Varki NM, Yu A, Staffileno LK, Reisfeld RA.
Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients.
Cancer Res. 1984 Dec ;44(12 Pt 1):5914-20
PMID: 6498849
3 Cheresh DA, Rosenberg J, Mujoo K, Hirschowitz L, Reisfeld RA.
Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis.
Cancer Res. 1986 Oct ;46(10):5112-8
PMID: 3019521
4 Cheresh DA, Pierschbacher MD, Herzig MA, Mujoo K.
Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins.
J Cell Biol. 1986 Mar ;102(3):688-96
PMID: 3005335