RM2
| Antibody ID | AN0279 |
|---|
| Epitope ID | EP0097 |
|---|---|
| Epitope name | GalNAc Disialyl Lc4 (Hexasaccharide) |
| Recognition region | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-3)[NeuAc(a2-6)]GlcNAc(b1-3)Gal-R |
| Immunoprecipitation | |
| Immunoblot | [3*][2][1*] |
| ELISA/RIA | [3*][1*] |
| Flow cytometry | |
| Histochemistry | [2] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | TOS-1/human renal cell carcinoma[3*] |
| Availability | |
| Applications |
| 1 | Ito A, Levery SB, Saito S, Satoh M, Hakomori S. A novel ganglioside isolated from renal cell carcinoma. J Biol Chem. 2001 May 18;276(20):16695-703 PMID: 11278988 |
|---|---|
| 2 | Saito S, Egawa S, Endoh M, Ueno S, Ito A, Numahata K, Satoh M, Kuwao S, Baba S, Hakomori S, Arai Y. RM2 antigen (beta1,4-GalNAc-disialyl-Lc4) as a new marker for prostate cancer. Int J Cancer. 2005 May 20;115(1):105-13 PMID: 15704108 |
| 3 | Saito S, Levery SB, Salyan ME, Goldberg RI, Hakomori S. Common tetrasaccharide epitope NeuAc alpha 2-->3Gal beta 1-->3(Neu-Ac alpha 2-->6)GalNAc, presented by different carrier glycosylceramides or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities. J Biol Chem. 1994 Feb 25;269(8):5644-52 PMID: 7509790 |