MBr1

Antibody IDAN0478
Epitope ID EP0253
Epitope nameBlood Group H Type 3
Recognition regionFuc(a1-2)Gal(b1-3)GalNAc(a1-)-R
Fuc(a1-2)Gal(b1-3)GalNAc(b1-)-R
Immunoprecipitation
Immunoblot[2*][1]
ELISA/RIA
Flow cytometry
Histochemistry
Comment
Epitope ID EP0254
Epitope nameBlood Group H Type 4
Recognition regionFuc(a1-2)Gal(b1-3)GalNAc(a1-)-R
Fuc(a1-2)Gal(b1-3)GalNAc(b1-)-R
Immunoprecipitation
Immunoblot[2*][3][4*][1]
ELISA/RIA[4*]
Flow cytometry
Histochemistry[3]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
ImmunogenMCF-7/human breast adenocarcinoma[5]
Availability
Applications
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1 Clausen H, Levery SB, Nudelman E, Tsuchiya S, Hakomori S.
Repetitive A epitope (type 3 chain A) defined by blood group A1-specific monoclonal antibody TH-1: chemical basis of qualitative A1 and A2 distinction.
Proc Natl Acad Sci U S A. 1985 Feb ;82(4):1199-203
PMID: 2579390
2 Clausen H, Levery SB, Kannagi R, Hakomori S.
Novel blood group H glycolipid antigens exclusively expressed in blood group A and AB erythrocytes (type 3 chain H). I. Isolation and chemical characterization.
J Biol Chem. 1986 Jan 25;261(3):1380-7
PMID: 3944091
3 Okada Y, Colnaghi MI, Tsuji T.
Type 4 chain H expression by bile ductules and hepatocytes in cirrhosis.
J Pathol. 1989 Apr ;157(4):329-38
PMID: 2469783
4 Bremer EG, Levery SB, Sonnino S, Ghidoni R, Canevari S, Kannagi R, Hakomori S.
Characterization of a glycosphingolipid antigen defined by the monoclonal antibody MBr1 expressed in normal and neoplastic epithelial cells of human mammary gland.
J Biol Chem. 1984 Dec 10;259(23):14773-7
PMID: 6501317
5 Mènard S, Tagliabue E, Canevari S, Fossati G, Colnaghi MI.
Generation of monoclonal antibodies reacting with normal and cancer cells of human breast.
Cancer Res. 1983 Mar ;43(3):1295-300
PMID: 6337705