VIM-2
General | Antibody | Glycoprotein | Glycolipid | Enzyme | ReferenceEpitope information of EP0019
| Epitope ID | EP0019 |
|---|---|
| Epitope name | VIM-2 |
| Structure |  |
| Sequence | Neu5Ac(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R |
| Aliases | CD65, CDw65, Sialyl Lewis i-X |
| History | A mouse monoclonal antibody,VIM-2,specific for human blood cells of myelomonocytic lineage,was found to bind to a series of minor gangliosides isolated from the cells of patients with chronic myelogenous leukemia(1985).[3][1*] |
| DB | GlyTouCan:G22418PV JCGGDB |
| Molecular weight | 1348.2 |
| Composition | (Fuc)1(Gal)3(GlcNAc)2(Neu5Ac)1 |
| Species | Homo sapiens |
| Tissue and Cellular distribution | myeloid cell |
| Subcellular distribution | |
| Developmental change | |
| Cell line | HL-60/human promyelocytic leukemia |
| Receptor | |
| Function | CDw65 have been shown to interact with the ELAM-1 molecule on activated endothelium.[2][4] |
| Diseases | |
| Application | |
| Comment |