Fucosyl GM1

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0049

Epitope IDEP0049
Epitope nameFucosyl GM1
Structure
SequenceFuc(a1-2)Gal(b1-3)GalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Aliases
HistoryFucosyl-GM1 was first isolated from bovine thyoid gland and was subsequently identified on small-cell lung cancers by using the monoclonal antibody F12.[3*][4][5][6]
DB GlyTouCan:G91532KA JCGGDB
Molecular weight1145.0(Cer)
Composition(Fuc)1(Gal)2(GalNAc)1(Glc)1(Neu5Ac)1(Cer)1
Species

Bos taurus[3*][4]
Homo sapiens[7][8]
Oryctolagus cuniculus[2]
Rattus norvegicus[9][10]
Tissue and Cellular distribution

cancer/hepatoma(rat)[9][10]
cancer/small-cell lung cancer(SCLC)(human)[7][8]
peripheral nerve(rabbit) [2]
spinal cord(rabbit)[2]
thyoid gland(bovine)[3*][4]
Subcellular distribution
Developmental change
Cell line

H4-II-E/rat hepatoma[10]
NC1 H128/human SCLC
NC1 H69/human SCLC
Receptor
Function
Diseases

small-cell lung cancer(SCLC)
hepatoma
Application
Comment