GlycoEpitope: show

GT1a alpha

Epitope information of EP0111

Epitope ID	EP0111
Epitope name	GT1a alpha
Structure
Sequence	Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Aliases	Chol-1 alpha-a
History	Cholinergic-specific antigens termed the Chol-1 family have been suggested to be of a ganglioside nature by Richardson et al. The chemical structure of Chol-1 alpha-a was determined for the first time, being as follows: IV3NeuAc III6NeuAc II3NeuAc-GgOse4 Cer.[2][3]
DB	GlyTouCan:G02149VR JCGGDB
Molecular weight	1872.7(Cer)
Composition	(Gal)2(GalNAc)1(Glc)1(Neu5Ac)4(Cer)1
Species	Bos taurus[3] Rattus norvegicus[4]
Tissue and Cellular distribution	brain(bovine)[3] central nervous system(rat)[4]
Subcellular distribution
Developmental change
Cell line
Receptor
Function	GT1a alpha was a cholinerginic-specific antigen.
Diseases
Application
Comment

Epitope ID

EP0111

Epitope name

GT1a alpha

Structure

Sequence

Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer

Aliases

Chol-1 alpha-a

History

Cholinergic-specific antigens termed the Chol-1 family have been suggested to be of a ganglioside nature by Richardson et al. The chemical structure of Chol-1 alpha-a was determined for the first time, being as follows: IV3NeuAc III6NeuAc II3NeuAc-GgOse4 Cer.[2][3]

GlyTouCan:G02149VR JCGGDB

Molecular weight

1872.7(Cer)

Composition

(Gal)2(GalNAc)1(Glc)1(Neu5Ac)4(Cer)1

Species

Bos taurus[3]
Rattus norvegicus[4]

Tissue and Cellular distribution

brain(bovine)[3]
central nervous system(rat)[4]

Subcellular distribution

Developmental change

Cell line

Receptor

Function

GT1a alpha was a cholinerginic-specific antigen.

Diseases

Application

Comment