Lewis x
General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference41 reference for EP0011
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| 1 | Izawa M, Kumamoto K, Mitsuoka C, Kanamori C, Kanamori A, Ohmori K, Ishida H, Nakamura S, Kurata-Miura K, Sasaki K, Nishi T, Kannagi R. Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer. Cancer Res. 2000 Mar 1;60(5):1410-6 PMID: 10728707 |
2 | Ohtani H, Fukushi Y, Orikasa S, Nagura H. Qualitative difference of subcellular localization of tumor-associated carbohydrate (Le(x)) antigens in renal cell carcinoma and normal kidney. J Histochem Cytochem. 1991 Apr ;39(4):479-84 PMID: 1672317 |
3 | Sittel C, Eckel HE, Damm M, von Pritzbuer E, Kvasnicka HM. Ki-67 (MIB1), p53, and Lewis-X (LeuM1) as prognostic factors of recurrence in T1 and T2 laryngeal carcinoma. Laryngoscope. 2000 Jun ;110(6):1012-7 PMID: 10852523 |
4 | Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. J Immunol. 1997 Aug 15;159(4):1917-29 PMID: 9257857 |
5 | Fukushi Y, Hakomori S, Nudelman E, Cochran N. Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain. J Biol Chem. 1984 Apr 10;259(7):4681-5 PMID: 6200484 |
6 | Nakayama J, Ota H, Katsuyama T, Kanai M, Taki T, Hirabayashi Y, Suzuki Y. Immunohistochemical demonstration of glycoconjugates bearing the type 2 chain-backbone structure in human fetal, normal and neoplastic gastrointestinal tract. Histochemistry. 1992 May ;97(4):303-10 PMID: 1618643 |
7 | Cooling LL, Zhang DS, Walker KE, Koerner TA. Detection in human blood platelets of sialyl Lewis X gangliosides, potential ligands for CD62 and other selectins. Glycobiology. 1995 Sep ;5(6):571-81 PMID: 8563144 |
8 | Karagenc L, Cinnamon Y, Ginsburg M, Petitte JN. Origin of primordial germ cells in the prestreak chick embryo. Dev Genet. 1996 ;19(4):290-301 PMID: 9023982 |
9 | Benharroch D, Dima E, Levy A, Ohana-Malka O, Ariad S, Prinsloo I, Mejirovsky E, Sacks M, Gopas J. Differential expression of sialyl and non-sialyl-CD15 antigens on Hodgkin-Reed-Sternberg cells: significance in Hodgkin's disease. Leuk Lymphoma. 2000 Sep ;39(1-2):185-94 PMID: 10975398 |
10 | Hakomori S, Nudelman E, Levery S, Solter D, Knowles BB. The hapten structure of a developmentally regulated glycolipid antigen (SSEA-1) isolated from human erythrocytes and adenocarcinoma: a preliminary note. Biochem Biophys Res Commun. 1981 Jun ;100(4):1578-86 PMID: 6117281 |
11 | Gooi HC, Feizi T, Kapadia A, Knowles BB, Solter D, Evans MJ. Stage-specific embryonic antigen involves alpha 1 goes to 3 fucosylated type 2 blood group chains. Nature. 1981 Jul 9;292(5819):156-8 PMID: 6165896 |
12 | Warren HS, Altin JG, Waldron JC, Kinnear BF, Parish CR. A carbohydrate structure associated with CD15 (Lewis x) on myeloid cells is a novel ligand for human CD2. J Immunol. 1996 Apr 15;156(8):2866-73 PMID: 8609406 |
13 | Eggens I, Fenderson B, Toyokuni T, Dean B, Stroud M, Hakomori S. Specific interaction between Lex and Lex determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells. J Biol Chem. 1989 Jun 5;264(16):9476-84 PMID: 2470757 |
14 | Azuma Y, Ito M, Taniguchi A, Matsumoto K. Expression of cell surface Lewis X and Y antigens and FUT4 mRNA is increased in Jurkat cells undergoing apoptosis. Biochim Biophys Acta. 2004 Jun 11;1672(3):157-63 PMID: 15182935 |
15 | Lenkei R, Bjork O, Ost A, Biberfeld P. Expression of CD15 as predictor of relapse in children with acute lymphoblastic leukemia of the pre-B type. Leuk Res. 1991 ;15(4):189-94 PMID: 1674292 |
16 | Nakayama F, Nishihara S, Iwasaki H, Kudo T, Okubo R, Kaneko M, Nakamura M, Karube M, Sasaki K, Narimatsu H. CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV. J Biol Chem. 2001 May 11;276(19):16100-6 PMID: 11278338 |
17 | Weninger W, Ulfman LH, Cheng G, Souchkova N, Quackenbush EJ, Lowe JB, von Andrian UH. Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels. Immunity. 2000 Jun ;12(6):665-76 PMID: 10894166 |
18 | Kudo T, Kaneko M, Iwasaki H, Togayachi A, Nishihara S, Abe K, Narimatsu H. Normal embryonic and germ cell development in mice lacking alpha 1,3-fucosyltransferase IX (Fut9) which show disappearance of stage-specific embryonic antigen 1. Mol Cell Biol. 2004 May ;24(10):4221-8 PMID: 15121843 |
19 | Stroud MR, Levery SB, Nudelman ED, Salyan ME, Towell JA, Roberts CE, Watanabe M, Hakomori S. Extended type 1 chain glycosphingolipids: dimeric Lea (III4V4Fuc2Lc6) as human tumor-associated antigen. J Biol Chem. 1991 May 5;266(13):8439-46 PMID: 2022659 |
20 | Kannagi R, Levery SB, Hakomori S. Lea-active heptaglycosylceramide, a hybrid of type 1 and type 2 chain, and the pattern of glycolipids with Lea, Leb, X (Lex), and Y (Ley) determinants in human blood cell membranes (ghosts). Evidence that type 2 chain can elongate repetitively but type 1 chain cannot. J Biol Chem. 1985 May 25;260(10):6410-5 PMID: 3997830 |
21 | Geyer A, Gege C, Schmidt RR. Calcium-Dependent Carbohydrate-Carbohydrate Recognition between Lewis(X) Blood Group Antigens This research was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie. Angew Chem Int Ed Engl. 2000 Sep 15;39(18):3245-3249 PMID: 11028065 |
22 | Hakomori S, Kannagi R. Glycosphingolipids as tumor-associated and differentiation markers. J Natl Cancer Inst. 1983 Aug ;71(2):231-51 PMID: 6576183 |
23 | Hakomori S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv Cancer Res. 1989 ;52:257-331 PMID: 2662714 |
24 | Marcus DM, Gilbert S, Sekine M, Suzuki A. Monoclonal antibodies that bind to galactosylgloboside (SSEA-3 antigen). Arch Biochem Biophys. 1988 May 1;262(2):620-5 PMID: 3364985 |
25 | Hirabayashi Y, Fujita SC, Kon K, Ando S. Characterization of a novel Le(x)-active ganglioside from chick intestinal tissues recognized by murine monoclonal antibody 188C1. J Biol Chem. 1991 Jun 5;266(16):10268-74 PMID: 1674743 |
26 | Urdal DL, Brentnall TA, Bernstein ID, Hakomori SI. A granulocyte reactive monoclonal antibody, 1G10, identifies the Gal beta 1-4 (Fuc alpha 1-3)GlcNAc (X determinant) expressed in HL-60 cells on both glycolipid and glycoprotein molecules. Blood. 1983 Nov ;62(5):1022-6 PMID: 6194834 |
27 | Saarinen J, Welgus HG, Flizar CA, Kalkkinen N, Helin J. N-glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells. Eur J Biochem. 1999 Feb ;259(3):829-40 PMID: 10092871 |
28 | Muroi K, Suda T, Nojiri H, Ema H, Amemiya Y, Miura Y, Nakauchi H, Singhal A, Hakomori S. Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. Blood. 1992 Feb 1;79(3):713-9 PMID: 1370643 |
29 | Singhal AK, Orntoft TF, Nudelman E, Nance S, Schibig L, Stroud MR, Clausen H, Hakomori S. Profiles of Lewisx-containing glycoproteins and glycolipids in sera of patients with adenocarcinoma. Cancer Res. 1990 Mar 1;50(5):1375-80 PMID: 2302702 |
30 | Holmes EH, Hakomori S, Ostrander GK. Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase. J Biol Chem. 1987 Nov 15;262(32):15649-58 PMID: 2960671 |
31 | Gooi HC, Hounsell EF, Edwards A, Majdic O, Knapp W, Feizi T. Differences in the fine specificities of monoclonal (Class A) antibodies to human myeloid cells. Clin Exp Immunol. 1985 Apr ;60(1):151-8 PMID: 2408796 |
32 | Huang LC, Brockhaus M, Magnani JL, Cuttitta F, Rosen S, Minna JD, Ginsburg V. Many monoclonal antibodies with an apparent specificity for certain lung cancers are directed against a sugar sequence found in lacto-N-fucopentaose III. Arch Biochem Biophys. 1983 Jan ;220(1):318-20 PMID: 6830241 |
33 | Cuttitta F, Rosen S, Gazdar AF, Minna JD. Monoclonal antibodies that demonstrate specificity for several types of human lung cancer. Proc Natl Acad Sci U S A. 1981 Jul ;78(7):4591-5 PMID: 6270685 |
34 | Holmes EH, Ostrander GK, Clausen H, Graem N. Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation. J Biol Chem. 1987 Aug 15;262(23):11331-8 PMID: 3112156 |
35 | Huang LC, Civin CI, Magnani JL, Shaper JH, Ginsburg V. My-1, the human myeloid-specific antigen detected by mouse monoclonal antibodies, is a sugar sequence found in lacto-N-fucopentaose III. Blood. 1983 May ;61(5):1020-3 PMID: 6187397 |
36 | Okada Y, Arima T, Nagashima H, Fukushi Y, Kannagi R, Kaizu T. Human hepatocellular carcinoma-associated changes of glycosphingolipids detected by two monoclonal antibodies FH2 and IB9. J Hepatol. 1986 ;2(3):430-40 PMID: 2424969 |
37 | Naarding MA, Ludwig IS, Groot F, Berkhout B, Geijtenbeek TB, Pollakis G, Paxton WA. Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes. J Clin Invest. 2005 Nov ;115(11):3256-64 PMID: 16239964 |
38 | Nomoto S, Muramatsu H, Ozawa M, Suganuma T, Tashiro M, Muramatsu T. An anti-carbohydrate monoclonal antibody inhibits cell-substratum adhesion of F9 embryonal carcinoma cells. Exp Cell Res. 1986 May ;164(1):49-62 PMID: 3754220 |
39 | Yoshinaga K, Muramatsu H, Muramatsu T. Immunohistochemical localization of the carbohydrate antigen 4C9 in the mouse embryo: a reliable marker of mouse primordial germ cells. Differentiation. 1991 Nov ;48(2):75-82 PMID: 1773918 |
40 | Muramatsu H, Kusano T, Sato M, Oda Y, Kobori K, Muramatsu T. Embryonic stem cells deficient in I beta1,6-N-acetylglucosaminyltransferase exhibit reduced expression of embryoglycan and the loss of a Lewis X antigen, 4C9. Glycobiology. 2008 Mar ;18(3):242-9 PMID: 18184719 |
41 | Ball ED, Graziano RF, Fanger MW. A unique antigen expressed on myeloid cells and acute leukemia blast cells defined by a monoclonal antibody. J Immunol. 1983 Jun ;130(6):2937-41 PMID: 6574189 |