Sialyl Lewis x
General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference53 reference for EP0012
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| 1 | Renkonen J, Tynninen O, Hayry P, Paavonen T, Renkonen R. Glycosylation might provide endothelial zip codes for organ-specific leukocyte traffic into inflammatory sites. Am J Pathol. 2002 Aug ;161(2):543-50 PMID: 12163379 |
2 | Cai S, Davis AE 3rd. Complement regulatory protein C1 inhibitor binds to selectins and interferes with endothelial-leukocyte adhesion. J Immunol. 2003 Nov 1;171(9):4786-91 PMID: 14568956 |
3 | Nakagoe T, Fukushima K, Sawai T, Tsuji T, Jibiki M, Nanashima A, Tanaka K, Yamaguchi H, Yasutake T, Ayabe H, Ishikawa H. Increased expression of sialyl Lewis(x) antigen in penetrating growth type A early gastric cancer. J Exp Clin Cancer Res. 2002 Sep ;21(3):363-9 PMID: 12385579 |
4 | Zhang K, Chuluyan HE, Hardie D, Shen DC, Larsen R, Issekutz A. Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells. Hybridoma. 1998 Oct ;17(5):445-56 PMID: 9873990 |
5 | Tamatani T, Suematsu M, Tezuka K, Hanzawa N, Tsuji T, Ishimura Y, Kannagi R, Toyoshima S, Homma M. Recognition of consensus CHO structure in ligands for selectins by novel antibody against sialyl Lewis X. Am J Physiol. 1995 Oct ;269(4 Pt 2):H1282-7 PMID: 7485559 |
6 | Akahori T, Yuzawa Y, Nishikawa K, Tamatani T, Kannagi R, Miyasaka M, Okada H, Hotta N, Matsuo S. Role of a sialyl Lewis(x)-like epitope selectively expressed on vascular endothelial cells in local skin inflammation of the rat. J Immunol. 1997 Jun 1;158(11):5384-92 PMID: 9164959 |
7 | Takaeda M, Yokoyama H, Segawa-Takaeda C, Wada T, Kobayashi K. High endothelial venule-like vessels in the interstitial lesions of human glomerulonephritis. Am J Nephrol. 2002 Jan ;22(1):48-57 PMID: 11919403 |
8 | Croce MV, Colussi AG, De Bravo MG, Price MR, Segal-Eiras A. Immunohistopathological characterizatin of spontaneous metastases in a human lung mucoepidermoid adenocarcinoma (HLMC) xenograft. Pathol Oncol Res. 1998 ;4(4):259-66 PMID: 9887355 |
9 | Tu L, Murphy PG, Li X, Tedder TF. L-selectin ligands expressed by human leukocytes are HECA-452 antibody-defined carbohydrate epitopes preferentially displayed by P-selectin glycoprotein ligand-1. J Immunol. 1999 Nov 1;163(9):5070-8 PMID: 10528213 |
10 | Mitsuoka C, Sawada-Kasugai M, Ando-Furui K, Izawa M, Nakanishi H, Nakamura S, Ishida H, Kiso M, Kannagi R. Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X. J Biol Chem. 1998 May 1;273(18):11225-33 PMID: 9556613 |
11 | Hanski C, Hanski ML, Zimmer T, Ogorek D, Devine P, Riecken EO. Characterization of the major sialyl-Lex-positive mucins present in colon, colon carcinoma, and sera of patients with colorectal cancer. Cancer Res. 1995 Feb 15;55(4):928-33 PMID: 7850810 |
12 | Grabowski P, Mann B, Mansmann U, Lovin N, Foss HD, Berger G, Scherubl H, Riecken EO, Buhr HJ, Hanski C. Expression of SIALYL-Le(x) antigen defined by MAb AM-3 is an independent prognostic marker in colorectal carcinoma patients. Int J Cancer. 2000 Oct 15;88(2):281-6 PMID: 11004681 |
13 | Symington FW, Holmes EH, Symington BE. Human epidermal keratinocyte expression of sialyl-Lewis X. J Invest Dermatol. 1992 Nov ;99(5):601-7 PMID: 1358980 |
14 | Takao S, Uchikura K, Yonezawa S, Shinchi H, Aikou T. Mucin core protein expression in extrahepatic bile duct carcinoma is associated with metastases to the liver and poor prognosis. Cancer. 1999 Nov 15;86(10):1966-75 PMID: 10570420 |
15 | Fernandez-Rodriguez J, Dwir O, Alon R, Hansson GC. Tumor cell MUC1 and CD43 are glycosylated differently with sialyl-Lewis a and x epitopes and show variable interactions with E-selectin under physiological flow conditions. Glycoconj J. 2001 Nov ;18(11-12):925-30 PMID: 12820726 |
16 | Izawa M, Kumamoto K, Mitsuoka C, Kanamori C, Kanamori A, Ohmori K, Ishida H, Nakamura S, Kurata-Miura K, Sasaki K, Nishi T, Kannagi R. Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer. Cancer Res. 2000 Mar 1;60(5):1410-6 PMID: 10728707 |
17 | Kannagi R. Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer. Glycoconj J. 1997 Aug ;14(5):577-84 PMID: 9298690 |
18 | Steegmaier M, Levinovitz A, Isenmann S, Borges E, Lenter M, Kocher HP, Kleuser B, Vestweber D. The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor. Nature. 1995 Feb 16;373(6515):615-20 PMID: 7531823 |
19 | Moore KL, Eaton SF, Lyons DE, Lichenstein HS, Cummings RD, McEver RP. The P-selectin glycoprotein ligand from human neutrophils displays sialylated, fucosylated, O-linked poly-N-acetyllactosamine. J Biol Chem. 1994 Sep 16;269(37):23318-27 PMID: 7521878 |
20 | Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. J Immunol. 1997 Aug 15;159(4):1917-29 PMID: 9257857 |
21 | Kamata T, Yoneumura Y, Sugiyama K, Yamaguchi A, Miwa K, Miyazaki I. [Monoclonal antibody NCC-ST-439 in gastric cancer tissue] Nippon Geka Gakkai Zasshi. 1989 Feb ;90(2):222-7 PMID: 2747606 |
22 | Narita T, Funahashi H, Satoh Y, Watanabe T, Sakamoto J, Takagi H. Association of expression of blood group-related carbohydrate antigens with prognosis in breast cancer. Cancer. 1993 May 15;71(10):3044-53 PMID: 8490832 |
23 | Ogawa J, Inoue H, Koide S. Expression of alpha-1,3-fucosyltransferase type IV and VII genes is related to poor prognosis in lung cancer. Cancer Res. 1996 Jan 15;56(2):325-9 PMID: 8542587 |
24 | Seko Y, Enokawa Y, Tamatani T, Kannagi R, Yagita H, Okumura K, Yazaki Y. Expression of sialyl Lewis(X) in rat heart with ischaemia/reperfusion and reduction of myocardial reperfusion injury by a monoclonal antibody against sialyl Lewis(X) J Pathol. 1996 Nov ;180(3):305-10 PMID: 8958810 |
25 | Priest R, Bird MI, Malhotra R. Characterization of E-selectin-binding epitopes expressed by skin-homing T cells. Immunology. 1998 Aug ;94(4):523-8 PMID: 9767440 |
26 | Farmer RW, Richtsmeier WJ, Scher RL. Identification of sialyl Lewis-x in squamous cell carcinoma of the head and neck. Head Neck. 1998 Dec ;20(8):726-31 PMID: 9790295 |
27 | Tsuji T, Kimura Y, Murakami T, Sasaki K, Shinozaki F. [An immunohistochemical evaluation of Warthin's tumor using the monoclonal anti-human lung adenocarcinoma antibody KM-93 and the anti-human gastric carcinoma antibody KM-231] Gan No Rinsho. 1990 Jun ;36(7):783-6 PMID: 2355463 |
28 | Tsuzi T, Shinozaki F, Yamada K, Mori M. Immunohistochemical detection of human lung and gastric cancer antigen in human salivary gland tumors. Anticancer Res. 1989 Mar ;9(2):327-39 PMID: 2665633 |
29 | Kimura N, Mitsuoka C, Kanamori A, Hiraiwa N, Uchimura K, Muramatsu T, Tamatani T, Kansas GS, Kannagi R. Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of alpha1-->3 fucosyltransferase VII and newly cloned GlcNAcbeta:6-sulfotransferase cDNA. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4530-5 PMID: 10200296 |
30 | Lowe JB, Stoolman LM, Nair RP, Larsen RD, Berhend TL, Marks RM. ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA. Cell. 1990 Nov 2;63(3):475-84 PMID: 1699667 |
31 | Phillips ML, Nudelman E, Gaeta FC, Perez M, Singhal AK, Hakomori S, Paulson JC. ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. Science. 1990 Nov 23;250(4984):1130-2 PMID: 1701274 |
32 | Walz G, Aruffo A, Kolanus W, Bevilacqua M, Seed B. Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells. Science. 1990 Nov 23;250(4984):1132-5 PMID: 1701275 |
33 | Kannagi R, Fukushi Y, Tachikawa T, Noda A, Shin S, Shigeta K, Hiraiwa N, Fukuda Y, Inamoto T, Hakomori S, et al. Quantitative and qualitative characterization of human cancer-associated serum glycoprotein antigens expressing fucosyl or sialyl-fucosyl type 2 chain polylactosamine. Cancer Res. 1986 May ;46(5):2619-26 PMID: 3008996 |
34 | Ohmori K, Takada A, Ohwaki I, Takahashi N, Furukawa Y, Maeda M, Kiso M, Hasegawa A, Kannagi M, Kannagi R. A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells. Blood. 1993 Nov 1;82(9):2797-805 PMID: 7693048 |
35 | Ohmori K, Yoneda T, Ishihara G, Shigeta K, Hirashima K, Kanai M, Itai S, Sasaoki T, Arii S, Arita H, et al. Sialyl SSEA-1 antigen as a carbohydrate marker of human natural killer cells and immature lymphoid cells. Blood. 1989 Jul ;74(1):255-61 PMID: 2568858 |
36 | Sawada M, Takada A, Ohwaki I, Takahashi N, Tateno H, Sakamoto J, Kannagi R. Specific expression of a complex sialyl Lewis X antigen on high endothelial venules of human lymph nodes: possible candidate for L-selectin ligand. Biochem Biophys Res Commun. 1993 May 28;193(1):337-47 PMID: 7684905 |
37 | Maly P, Thall A, Petryniak B, Rogers CE, Smith PL, Marks RM, Kelly RJ, Gersten KM, Cheng G, Saunders TL, Camper SA, Camphausen RT, Sullivan FX, Isogai Y, Hindsgaul O, von Andrian UH, Lowe JB. The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell. 1996 Aug 23;86(4):643-53 PMID: 8752218 |
38 | Clark RA, Fuhlbrigge RC, Springer TA. L-Selectin ligands that are O-glycoprotease resistant and distinct from MECA-79 antigen are sufficient for tethering and rolling of lymphocytes on human high endothelial venules. J Cell Biol. 1998 Feb 9;140(3):721-31 PMID: 9456330 |
39 | Suematsu M, Suzuki H, Tamatani T, Iigou Y, DeLano FA, Miyasaka M, Forrest MJ, Kannagi R, Zweifach BW, Ishimura Y, et al. Impairment of selectin-mediated leukocyte adhesion to venular endothelium in spontaneously hypertensive rats. J Clin Invest. 1995 Oct ;96(4):2009-16 PMID: 7560094 |
40 | Mitsuoka C, Kawakami-Kimura N, Kasugai-Sawada M, Hiraiwa N, Toda K, Ishida H, Kiso M, Hasegawa A, Kannagi R. Sulfated sialyl Lewis X, the putative L-selectin ligand, detected on endothelial cells of high endothelial venules by a distinct set of anti-sialyl Lewis X antibodies. Biochem Biophys Res Commun. 1997 Jan 23;230(3):546-51 PMID: 9015359 |
41 | Galustian C, Lawson AM, Komba S, Ishida H, Kiso M, Ten Feizi. Sialyl-Lewisx Sequence 6-O-Sulfated at N-Acetylglucosamine Rather Than at Galactose Is the Preferred Ligand for l-Selectin and De-N-acetylation of the Sialic Acid Enhances the Binding Strength Biochem Biophys Res Commun. 1997 Nov 26;240(3):748-51 PMID: 9398638 |
42 | Zenita K, Hirashima K, Shigeta K, Hiraiwa N, Takada A, Hashimoto K, Fujimoto E, Yago K, Kannagi R. Northern hybridization analysis of VH gene expression in murine monoclonal antibodies directed to cancer-associated ganglioside antigens having various sialic acid linkages. J Immunol. 1990 Jun 1;144(11):4442-51 PMID: 2111348 |
43 | Fukushi Y, Nudelman E, Levery SB, Hakomori S, Rauvala H. Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6). J Biol Chem. 1984 Aug 25;259(16):10511-7 PMID: 6469974 |
44 | Dohi T, Nemoto T, Ohta S, Shitara K, Hanai N, Nudelman E, Hakomori S, Oshima M. Different binding properties of three monoclonal antibodies to sialyl Le(x) glycolipids in a gastric cancer cell line and normal stomach tissue. Anticancer Res. 1993 Sep ;13(5A):1277-82 PMID: 8239497 |
45 | Croce MV, Isla-Larrain M, Tur R, Rabassa ME, Segal-Eiras A. Antigenic differences between metastatic cells in bone marrow and primary tumours and the anti-MUC1 humoral immune response induced in breast cancer patients. Clin Exp Metastasis. 2004 ;21(2):139-47 PMID: 15168731 |
46 | Shitara K, Hanai N, Yoshida H. Distribution of lung adenocarcinoma-associated antigens in human tissues and sera defined by monoclonal antibodies KM-52 and KM-93. Cancer Res. 1987 Mar 1;47(5):1267-72 PMID: 3545444 |
47 | Hanai N, Shitara K, Yoshida H. Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung. Cancer Res. 1986 Sep ;46(9):4438-43 PMID: 3731100 |
48 | Fukushima K, Hirota M, Terasaki PI, Wakisaka A, Togashi H, Chia D, Suyama N, Fukushi Y, Nudelman E, Hakomori S. Characterization of sialosylated Lewisx as a new tumor-associated antigen. Cancer Res. 1984 Nov ;44(11):5279-85 PMID: 6386148 |
49 | Muroi K, Suda T, Nojiri H, Ema H, Amemiya Y, Miura Y, Nakauchi H, Singhal A, Hakomori S. Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. Blood. 1992 Feb 1;79(3):713-9 PMID: 1370643 |
50 | Dohi T, Abe K, Ohshiba S, Yamaguchi K, Oshima M. Immunohistological and biochemical detection of fucosylated polylactosamine antigen with monoclonal antibody ACFH18 in gastric cancer and normal gastric mucosa. Jpn J Cancer Res. 1990 Jun ;81(6-7):676-81 PMID: 2119368 |
51 | Fukushi Y, Kannagi R, Hakomori S, Shepard T, Kulander BG, Singer JW. Location and distribution of difucoganglioside (VI3NeuAcV3III3Fuc2nLc6) in normal and tumor tissues defined by its monoclonal antibody FH6. Cancer Res. 1985 Aug ;45(8):3711-7 PMID: 4016748 |
52 | Croce MV, Isla-Larrain M, Rabassa ME, Demichelis S, Colussi AG, Crespo M, Lacunza E, Segal-Eiras A. Lewis x is highly expressed in normal tissues: a comparative immunohistochemical study and literature revision. Pathol Oncol Res. 2007 ;13(2):130-8 PMID: 17607374 |
53 | Akamine S, Nakagoe T, Sawai T, Tsuji T, Tanaka K, Hidaka S, Shibasaki S, Nanashima A, Yamaguchi H, Nagayasu T, Yasutake T. Differences in prognosis of colorectal cancer patients based on the expression of sialyl Lewisa, sialyl Lewisx and sialyl Tn antigens in serum and tumor tissue. Anticancer Res. 2004 Jul ;24(4):2541-6 PMID: 15330211 |