Sialyl Lewis x-i

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0043

Epitope IDEP0043
Epitope nameSialyl Lewis x-i
Structure
SequenceNeu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-)-R
AliasesSialyl Lex-i, Sialyl SSEA-1 , SLX
History
DB GlyTouCan:G06597DS
Molecular weight1348.2
Composition(Fuc)1(Gal)3(GlcNAc)2(Neu5Ac)1
Species

Homo sapiens

Tissue and Cellular distribution

NK cell[4]
serum[5][3]

Subcellular distribution

Developmental change

Cell line

Receptor

E-selectin

Function

hematogenous metastasis
the progression of inflammation

Diseases

lung cancer
ovarian cancer
pancreatic adenocarcinoma

ApplicationThe monoclonal antibody,FH-6 is representative diagnostic agent for adenocarcinoma.
Comment