GlycoEpitope: show

Epitope ID	EP0043
Epitope name	Sialyl Lewis x-i
Structure
Sequence	Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-)-R
Aliases	Sialyl Le^x-i, Sialyl SSEA-1 , SLX
History
DB	GlyTouCan:G06597DS
Molecular weight	1348.2
Composition	(Fuc)1(Gal)3(GlcNAc)2(Neu5Ac)1
Species	Homo sapiens
Tissue and Cellular distribution	NK cell[4] serum[5][3]
Subcellular distribution
Developmental change
Cell line
Receptor	E-selectin
Function	hematogenous metastasis the progression of inflammation
Diseases	lung cancer ovarian cancer pancreatic adenocarcinoma
Application	The monoclonal antibody,FH-6 is representative diagnostic agent for adenocarcinoma.
Comment

Epitope ID

EP0043

Epitope name

Sialyl Lewis x-i

Structure

Sequence

Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-)-R

Aliases

Sialyl Le^x-i, Sialyl SSEA-1 , SLX

History

Molecular weight

1348.2

Composition

(Fuc)1(Gal)3(GlcNAc)2(Neu5Ac)1

Species

Homo sapiens

Tissue and Cellular distribution

NK cell[4]
serum[5][3]

Subcellular distribution

Developmental change

Cell line

Receptor

E-selectin

Function

hematogenous metastasis
the progression of inflammation

Diseases

lung cancer
ovarian cancer
pancreatic adenocarcinoma

Application

The monoclonal antibody,FH-6 is representative diagnostic agent for adenocarcinoma.

Comment