Heparan Sulfate
General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference3 biosynthetic enzyme for EP0086
| Name | Reaction |
|---|---|
| Exostosin-1,Exostosin-2 | GlcNAc(a1-4)GlcA + UDP-GlcA = GlcA(b1-4)GlcNAc(a1-4)GlcA + UDP (EC 2.4.1.225) GlcA(b1-4)GlcNAc + UDP-GlcNAc = GlcNAc(a1-4)GlcA(b1-4)GlcNAc + UDP (EC 2.4.1.224) |
| NDST-1 | -[GlcA(b1-4) GlcNAc]n- + PAPS = -{GlcA(b1-4)[HSO3(-6)]GlcN} n- + PAP |
| Name | Exostosin-1 |
|---|---|
| Reaction | GlcNAc(a1-4)GlcA + UDP-GlcA = GlcA(b1-4)GlcNAc(a1-4)GlcA + UDP (EC 2.4.1.225) GlcA(b1-4)GlcNAc + UDP-GlcNAc = GlcNAc(a1-4)GlcA(b1-4)GlcNAc + UDP (EC 2.4.1.224) |
| Description | Multiple exostoses protein 1/EXT1 |
| EC | EC 2.4.1.224 |
| DB | NCBI/Gene Swissprot/TrEMBL |
| Gene deficient organisms | |
| Comment | |
| Name | Exostosin-2 |
| Reaction | GlcNAc(a1-4)GlcA + UDP-GlcA = GlcA(b1-4)GlcNAc(a1-4)GlcA + UDP (EC 2.4.1.225) GlcA(b1-4)GlcNAc + UDP-GlcNAc = GlcNAc(a1-4)GlcA(b1-4)GlcNAc + UDP (EC 2.4.1.224) |
| Description | Multiple exostoses protein 2/EXT2 |
| EC | EC 2.4.1.224 |
| DB | NCBI/Gene Swissprot/TrEMBL |
| Gene deficient organisms | [37] |
| Comment | |
| Name | NDST-1 |
| Reaction | -[GlcA(b1-4) GlcNAc]n- + PAPS = -{GlcA(b1-4)[HSO3(-6)]GlcN} n- + PAP |
| Description | N-deacetylase/N-sulfotransferase(heparan glucosaminyl)1 |
| EC | EC 2.8.2.8 |
| DB | NCBI/Gene Swissprot/TrEMBL |
| Gene deficient organisms | |
| Comment | |