Disialyl Lewis a

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

4 biosynthetic enzyme for EP0040

NameReaction
ST3Gal IV Gal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP
ST6GalNAc V,ST6GalNAc VI Neu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GlcNAc(b1-)-R + CMP
FUT3 Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GlcNAc(b1-)-R + GDP-Fuc = Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)][Fuc(a1-4)]GlcNAc(b1-)-R + GDP
NameST3Gal IV
ReactionGal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP
Descriptionalpha-2,3-sialyltransferase ST3Gal IV / SiaT4c
ECEC 2.4.99.-
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT29
Gene deficient organisms
Comment
NameST6GalNAc V
ReactionNeu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GlcNAc(b1-)-R + CMP
Descriptionalpha-2,6-sialyltransferase ST6GalNAc V / SiaT7e
ECEC 2.4.99.-
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT29
Gene deficient organisms
Comment
NameST6GalNAc VI
ReactionNeu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GlcNAc(b1-)-R + CMP
Descriptionalpha-2,6-sialyltransferase ST6GalNAc VI / SiaT7f
ECEC 2.4.99.-
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT29
Gene deficient organisms
Comment
NameFUT3
ReactionNeu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GlcNAc(b1-)-R + GDP-Fuc = Neu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)][Fuc(a1-4)]GlcNAc(b1-)-R + GDP
Descriptionalpha1-3/4FUT / Galactoside 3(4)-L-fucosyltransferase / Blood group Lewis alpha-4-fucosyltransferase / Lewis FT / Fucosyltransferase 3
ECEC 2.4.1.65
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT10
Gene deficient organisms
Comment

0 degradation enzyme for EP0040